3(0=Paved, 6=Very Difficult 4WD) Lots of rocks and potholes that require high clearance. 4WD is nice to have though not strictly required and a short wheelbase is not required. The parking area is basically just a meadow. You could camp at/near the trailhead if desired. No bathrooms or other facilities.
From Twin Lakes drive approximately 8.1 miles west on Colorado State Highway 82 towards Independence Pass. You will reach the La Plata Trailhead. Turn left at the trailhead onto Forest Road 391 and drive 2.7 miles on the rough dirt road before turning left again on Forest Road 382. Drive 1.7 miles to the Sayres Gulch Trailhead.